Precision Medicine(2017/10~2022/9)
“Precision Medicine” is the new concept based on the recent research progress. Precision Medicine will divide patients into certain subgroups and provide the most optimal treatment for each subgroup. We have conducted research and development for cancer treatment and diagnosis, including exploration of biomarkers to set patients into appropriate subgroups and establishment of evaluation models to predict the efficacy of drugs.
Main research participants (affiliation and position at the time)
- Hideyuki SAYA (Professor, Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine)
- Research field: Cancer Stem Cells, Cancer Heterogeneity
- Yutaka KAWAKAMI (Professor, Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine)
- Research Field: Cancer Immunity, Liquid Biopsy
- Hiroshi NISHIHARA (Professor, Genomics Unit, Keio Cancer Center, Keio University School of Medicine)
- Research Field: Cancer Genome Diagnosis
- Takeru FUNAKOSHI (Associate Professor, Department of Dermatology, Keio University School of Medicine)
- Research Field: Dermatological tumor
Publication
Role of androgen signaling in androgen receptor-positive extramammary Paget's disease: Establishment of organoids and their biological analysis as a novel therapeutic target.
Nakamura Y, Mizukami H, Tanese K, Fusumae T, Hirai I, Amagai M, Takamatsu R, Nakamura K, Nishihara H, Takimoto T, Ueno M, Saya H, Funakoshi T.
J Dermatol Sci. 112:23-30 (2023)