Designed Medical Device(2017/10-2022/9)

“Personalized Medicine” is the upcoming societal demand to contribute to extend healthy life expectancy.  We have focused on the creation of personalized medicine that satisfies clinical challenge and economic rationality through regenerative medicine, biomechanics, and digital imaging. This project contained two major R&D area; the digital domain and the regenerative medicine domain. The digital domain was centered on development of information technology and medical applications of 3D printing technology. The regenerative medicine domain aimed to integrate cell culture and material technologies. We have collaborated with many doctors in various medical departments. Through this project, two start-up companies were born.

Main research participants (affiliation and position at the time)

Masaya NAKAMURA (Professor, Department of Orthopedic Surgery, Keio University School of Medicine)
Research Field: Biomechanics, Regenerative medicine

Masahiro JINZAKI (Professor, Department of Radiology, Keio University School of Medicine)
Research Field: Digital imaging

Hiroshi YAGI (Assistant Professor, Department of General and Gastroenterological Surgery)
Research Field: Biomaterials

Start-up companies born from this project

Grace Imaging, Inc.
Matri Surge Co., Ltd.


Injectable extracellular matrix hydrogels contribute to native cell infiltration in a rat partial nephrectomy model.
Kushige H, Amano Y, Yagi H, Morisaku T, Kojima H, Satou A, Hamada K, Kitagawa Y.
J Biomed Mater Res B Appl Biomater. 111:184-193 (2023).